“ Welcome to OpenDEL™ ” HitGen OpenDEL™ Facilitate internal management and customer communication, enhance customer stickiness, improve customer experience, and expand influence. Learn More
News 15 May 2025 Latest Progress of DELLatest Progress of DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process. Learn More Papers 15 May 2025 Latest Progress of DELLatest Progress of DELLatest DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process. Learn More Activity 15 May 2025 Latest Progress of DELLatest Progress of DELLatest Progress of DEL DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process. Learn More News 1 December 2024 Latest Progress of DELLatest DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process.DNA-encoded chemical libraries (DEL) is a technology that involves the synthesis and conjugation of chemical compounds to DNA barcodes (Figure 1). This enables affinity screening against targets with billions of molecules, followed by deconvolution through high-throughput sequencing. Boosted by recent development of the next-generation sequencing technology, DEL aims to accelerate the drug discovery process. Learn More
OpenDEL™ Kit Starting a journey to access the vast DEL space The Kit50 Libraries3Bn compounds10 DEL samplesTo AccessFully enumerated moleculesBuilding Block StructuresDNA Codon SequencesScaffolds InformationNo Structure Disclosure FeeNo Structure Disclosure Fee
OpenDEL™ Screening OpenDEL™ screening is carried out by our team of experienced professionals, proficient in handling over 50 different target types including protein-protein interactions, kinases, enzymes, transcription factors, and RNA targets. Our team typically completes the screening experiments within 1-2 weeks. For more information and to explore detailed stories about our featured target types, click on the images below. We plan to release similar articles for other target classes in the future.
OpenDEL™ Sequencing HitGen offers high-quality sequencing services powered by two Illumina platforms (NextSeq2000 and NovaSeq6000) and one MGI platform (MGISEQ-2000), supported by 8 versatile flow cell types. Our flexible solutions cover a wide range of sequencing capacities, from 400M to 10,000M reads, tailored to your specific needs. With an average Q30 score exceeding 92% and a turnaround time of under two days, we deliver both speed and reliability for your research. In addition to DNA-encoded library (DEL) sequencing, we also provide multi-omics sequencing and data analysis services.
OpenDEL™ Hit Proposal Analyzing DEL selection data and choosing the right compounds for follow-up necessitates multidisciplinary expertise encompassing biology, computational science, and chemistry. This includes a deep understanding of the experimental design and mechanisms of action (MOAs) in biology, data processing and analysis in computational science, and aspects of both synthetic and DEL chemistry
OpenDEL™ Off-DNA Synthesis Our traditional synthesis service excels at recreating complex chemical structures derived from various DELs. We offer diverse options, including traditional chemistry synthesis service and high-throughput synthesis service. A. Traditional Chemical Synthesis @ HitGen B. High Throughput Chemical Synthesis @ HitGen‘s